This ZBrush sculpt is my take on one of Resident Evil's more popular bio-weapon, the Tyrant.

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Their usual trait of a Tyrant is that they possess humanoid bodies with certain parts being weaponized via mutation. I followed this rule and slightly taking it up a notch by including two different mutation themes on the body, monstrous spikes on the right side of his body and clustering tendrils on the left. 

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Sculpted in ZBrush.

Retopo-ed in Maya. 

Textured and rendered in Substance Painter.